الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Preeclampsia is a major cause of maternal and perinatal mortality with estimated incidence of 3-14 % of all pregnancies worldwide (Sibai et al.,2005). Several studies have suggested vascular endothelial dysfunction and platelets as important contributors in the pathophysiology of preeclampsia (Wang et al., 2004; Stekkinger et al.,2009 ;Varol et al.,2010). We designed this study to assess potential role of platelet reactivity and soluble E-selectin in pathogenesis of preeclampsia and to evaluate levels of sE-selectin as a predictor of preeclampsia. To achieve these aims, 85 pregnant women were categorized into two groups: control group comprises 40 Healthy pregnant women and patient group comprises 45 pregnant women with preeclampsia after 20 weeks of pregnancy. All patients and controls were subjected to thorough history taking and complete physical examination, laboratory investigations including, complete blood picture, liver function tests, kidney function test, uric acid test, complete urine analysis, soluble E-selectin estimation and collagen and ADP induced platelets aggregometry.