الفهرس 
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Abstract
The purpose of this study was to evaluate the performance of ACP containing pit and fissure sealant through clinical and laboratory study. Fifty patients with two first permanent molars indicated for pit and fissure sealant and scored 2 on ICDAS II, ranging in age from 7 to 10 years were selected from the outpatient clinic of the Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Alexandria University. Each patient had a history of at least one decayed or restored primary tooth in the former 2 years denoting moderate to high caries risk.
After obtaining parent’s consent, assessment of the molars under study with DIAGNOdent pen was performed. A preoperative reading ranging from 20-30 at the depth of the fissure was obtained and another reading was obtained at the mesiopalatal or mesiolingual cusp tips. The 50 patients were divided into two groups according to the sealant applied; group I (Aegis®, ACP containing sealant) and group II (Fisseal®, Fluoride containing sealant). After sealant application, a baseline reading was obtained at both the sealant/ tooth interface and at the relevant cusp tip.
Follow up was done at 3, 6, 9 and 12 months. Clinical examination was performed within each follow up visit to assess demineralization/ remineralization processes of the enamel using DIAGNOdent and evaluating sealant retention. Intervention was performed in case of caries progression, where the patient was scheduled for restoration.
Comparison was performed between the two groups. The results of this study revealed that for both groups, the effect on remineralization at the sealant/ tooth interface was not apparent. On the other hand, both ACP &