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Abstract High ligation allows for en bloc dissection of the lymph node metastases at and around the origin of the IMA; high ligation can be performed safely and does not increase the risk of anastomotic leak after surgery for colorectal cancers and also high ligation allows for a tension-free low anterior or coloanal anastomosis to be performed more easily. With the high lymph node harvest in high ligation, there will be better disease prognosis. Also, it can reduce the stage migration phenomenon, thus accurately predicting the outcome and this will lead to improved node retrieval rates and accuracy of tumor staging and can identify the cases that might require adjuvant chemotherapy. High ligation enables both identification and preservation of the sympathetic nerves and is an important component of total mesorectal excision. All of these items are well recognized ultimately to avoid tumor recurrence and the optimal extent of node dissection should be clarified and adjuvant therapies should be discussed based on the accurate staging. Thus, in colorectal cancer surgery high ligation should be the preferred method. Future high powered and well-designed randomized clinical trials are then needed to draw definitive conclusion on this dilemma. |