الفهرس 
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Abstract
This thesis includes three chapters. The first chapter is the introduction which comprises a review of the chemistry of the different types of pyrazolopyrimidines. The most important methods of synthesis of these compounds as well as their reactions and their biological activity are considered.
The second chapter is devoted to a discussion of the original work of the candidate regarding the synthesis of some pyrazolo[1,5-c]pyrimidinethiones as well as study of their reactions. Thus, a series of 5-aryl-2-phenyl-6H- pyrazolo[1,5-c]pyrimidine-7-thiones (99a-c) were prepared by a new route involving the reaction of the respective 1,5- diarylpent-1-yne-3,5-diones (98a-c) with thiosemicarbazide in ethanol. The mechanism of their formation was discussed. The structure of the pyrazolo[1,5-c]pyrimidinethiones was fully established besides elemental analyses by a study of their spectral characteristics including infrared,
electronic, 1Hnmr and mass spectra. While the infrared spectra of these compounds showed that, in the solid state, they exist predominantly in the thione form (99A), their 1Hnmr spectra in DMSO-d, indicated some contribution of the thiol form (993). Their mass spectra gave a relatively intense molecular ion peaks. Three dissociation routes were.