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Abstract Disseminated intravascular coagulation (DIC) is a rare, life-threatening condition that prevents blood from clotting normally. The blood clots reduce blood flow and can block blood from reaching bodily organs. This increased clotting can use up the blood’s platelets and clotting factors. Fewer platelets and clotting factors available result in excessive bleeding. When the proteins used in your normal clotting process become overly active, it can cause DIC. Infection, severe trauma (i.e., brain injuries, crushing injuries) inflammation, surgery, and cancer are all known to contribute to this condition. Bleeding, sometimes from multiple locations on the body, is one of the more common symptoms of DIC. Bleeding from the mucosa tissue (in the mouth and nose), and bleeding from other external areas may occur. In addition, DIC may also cause internal bleeding. DIC may be identified through various tests related to your levels of platelets, clotting factors and other blood components. However, there is not a standard procedure. Some tests that may be conducted if your doctor suspects DIC. Like fibrin degradation product ,complete blood cell count (CBC) from a blood smear ,complete blood cell count (CBC) from sample ,platelet count ,partial thromboplastin time ,D-dimer test ,serum fibrinogen and prothrombin time. DIC treatment depends on what is causing the disorder. Treatment of the underlying condition is the main goal. To treat the clotting problem, you may be given an anticoagulant called heparin to reduce and prevent clotting. However, heparin may not be administered if you have a severe lack of platelets or are bleeding too excessively. People with acute DIC require hospitalization, often in an intensive care unit (ICU), where treatment will attempt to correct the problem causing the DIC while maintaining the function of the organs. |