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Abstract The present work was performed to study the effect of apramycin sulphate, ceftiofur sodium and garlic on E.coli infection through evaluation of hemogram, blood chemistry, immunity and associated lesions in chickens. One hundred and sixty one day old chicks were used in this study. The birds were divided into eight equal groups. group (1) was kept as normal control. group (2) supplemented with 5 % raw garlic from the age of one day old till 35 days old. group (3) was infected via the crop with E. coli O111 (3 X 108 CFU) at the age of 14 days for 2 successive days. group (4) was supplemented with 5 % raw garlic from one day old till 35 days old and infected via the crop with E.coli O111 (3 X 108 CFU) at the age of 14 days for 2 successive days. group (5) was infected via the crop with E.coli O111 (3 X 108 CFU) at the age of 14 days for 2 successive days then treated with apramycin sulphate (225 mg/L) for 3 successive days at age of 18 days. group (6) was infected via the crop with E.coli O111 (3 X 108 CFU) at the age of 14 days for 2 successive days then treated with ceftiofur sodium 2 mg/kg.b.wt. S/C for 3 successive at age of 18 days. group (7) was infected via the crop with E.coli O111 (3 X 108 CFU) at the age of 14 days for 2 successive days then treated with apramycin sulphate (225 mg/L) for 3 successive days at age of 18 days and supplemented with 5 % raw garlic from 18 days old till 35 days old. group (8) was infected via the crop with E.coli O111 (3 X 108 CFU) at the age of 14 days for 2 successive days then treated with ceftiofur sodium (2 mg/kg.b.wt. S/C) for 3 successive days at age of 18 days and supplemented with 5% raw garlic from 18 days old till 35 days old. |