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Abstract Spinal instability is a loosely used tenn resulting from a variety of causes affecting the lwnbar spine. The role of treatment in these cases is to rehabilitate a disabled patient. The role of fusion in the lwnbar spine instability is to stabilize the spine to make rehabilitation possible. In this study, 50 patients having spondylolithesis (3 7 of them were lytic and 13 were degenerative) were assessed clinically and radiologically to detect the main problems and their possible contributors so that a suitable decision is chosen. The clinical data were collected in a special sheet fonn covering all the important information and the radiological workup included: Plain X-ray C.T Myelograms MRl Discography, that was of great help for detecting the level of fusion The patients were divided into 3 groups. A. PLIF with iliac bone blocks (30 cases) B. PLIF using RAMPs (10 cases) C. 360” fusion with iliac bone blocks (I 0 cases) Intraoperatively, the blood loss, levels of fusion, operative time and complications were registered for comparison, and the instrumentation svstem was identical biomechanically in all patients com pan son Summary for better Climcally, the Henderson system was used together with the Steffee-Brantlgan radiological system for assessmg the patients postoperatively The patients then were followed up for about 22.4 months in group A 18 months in group B 20.3 months in group C Group B showed the best results: 90% excellent clinical results and 90% excellent fusion that was fast and solid owing to the load sharing of the RAMPs. Then follows group A when clinical assessment is used or group C ’t radiological assessment is the one used. TI1e most 1mportant for patients is the clinical outcome that makes PLIF the best choice for a fusion when both decompressiOn and stabilitv are needed While combined fusion is a good choice when decompression is not needed to avoid the virgin neural canaL |