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العنوان
Relationship between lipid profile and
coronary plaque burden (volume) and extent
of coronary atherosclerosis in symptomatic
statin naïve patients, detected by MDCT\
المؤلف
Elwasify, Tamer Moustafa.
هيئة الاعداد
باحث / Tamer Moustafa Elwasify
مشرف / Adel Gamal Hassanein
مشرف / Khaled AbdelAzeem Shokry
مناقش / Mohammed Abd Elkader Abdel Rehim
تاريخ النشر
2013.
عدد الصفحات
165P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة عين شمس - كلية الطب - القلب والاوعية الدموية
الفهرس
Only 14 pages are availabe for public view

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from 16

Abstract

Dyslipidemia is an important risk factor for coronary
artery disease. There is strong relationship between total
cholesterol or LDL cholesterol levels, HDLand risk for
coronary artery disease events.
In our study we used coronary MDCT scan to evaluate 100
patients of mean age 54.34 ± 11.04, 69% males presented with
symptoms suggestive of coronary artery disease (chest pain
syndrome) along with full fasting lipid profile analysis. All the
study population were statin naïve.
MDCT scan allowed to evaluate the number, site,
volume,extent and density of coronary artery plaques, more
over it allowed their classification according to the type of
plaques (calcified, or non-calcified) and significance of
stenosis.
We found that total serum cholesterol, LDL cholesterol
and serum triglycerides were higher in the subgroup having
non-calcified plaques than those with calcified ones and were
significantly higher in the subgroup with significant than those
with non-significant stenosis. These three parameters
demonstrated also had a highly significant negative correlation
with the mean density of the plaques. HDL cholesterol was lower in the subgroup having noncalcified
plaques than those with calcified ones and had a strong
negative correlation with the significance of stenosis; it also had
significant positive correlation with the mean density of the
plaques.
We also found that total serum cholesterol, LDL
cholesterol and serum triglycerides were significantly positively
correlated with the calcium score and extent of
atherosclerosis,where as HDL was significantly negatively
correlated with calcium score and the extent of atherosclerosis