الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
One of the main reasons that patients are admitted to an intensive care unit is to receive ventilatory support. The indications for mechanical ventilation are numerous. Despite improvement in the management of the critically ill ventilated patients, the mortality of these patients remains high. Mechanical ventilation is the cornerstone in managing patients in pediatric intensive care units, yet it has many side effects which could increase the mortality and the morbidity by itself. Long period of mechanical ventilation increases the probability of many side effects. On the other hand, premature extubation can increase the mortality, morbidity, mechanical ventilation days and hospital stay.
The aim of this study was to evaluate the accuracy of some parameters in predicting extubation outcome in mechanically ventilated infants and children with primary lung diseases.
195 infant and child were included in the study from 2009-2012 .These infants and children received mechanical ventilation due to primary lung disease and were ventilated for more than 24 hrs.
All patients were subjected to: Thorough history taking and clinical examination, daily screening for ready to wean criteria and spontaneous breathing trial (SBT). Weaning predicators were measured before SBT, 30 minutes and 120 minutes after the start of SBT. Extubation was done for all patients after 120 minutes of SBT and all patients were followed for success or failure of extubation.
The results showed that both SBT 30 and SBT 120 had similar sensitivity, specificity, positive predictive value and negative predictive value.
The weaning parameters measured PaO2/FiO2, dynamic compliance, rapid shallow breathing index and P0.1 had similar sensitivities and specificities; 30 minutes and 120 minutes of the SBT.
The study concluded that SBT of 30 minutes and of 120 minutes are equivalent in predicting extubation outcome.
The recommendation was to use SBT 30 minutes in testing weaning readiness as it will save the time of busy intensive care staff.