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العنوان
Occurrence and Molecular Detection of Extended Spectrum Beta Lactamases in Clinical Isolates of Pseudomonas Species /
المؤلف
Hashem, Hany Rashad Abd El Saber.
هيئة الاعداد
باحث / Hany Rashad Abd El Saber Hashem
مشرف / Salah El Din Mohamed Abdalla
مشرف / Alaa El-Din Mahmoud Shawky Hosney
مشرف / Nora Fahmy Mahmoud
الموضوع
Pharmaceutical Sciences. Microbiology. Immunology.
تاريخ النشر
2013.
عدد الصفحات
155 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة قناة السويس - كلية الصيدلة - العلوم الصيدلية
الفهرس
Only 14 pages are availabe for public view

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from 155

Abstract

Pseudomonas aeruginosa is the most common pathogen causing nosocomial infections. Extended spectrum β-lactamases (ESBLs) producing gram negative bacteria are an increasing problem worldwide. A total of 48 pseudomonas aeruginosa strains were isolated and identified by API 20NE system. ESBL producing strains were detected phenotypically and genotypically. ESBL producers were 79.2% (38 out of 48 strains). PCR assay considered a gold standard method as it was detected all ESBL producers. However the phenotypic tests showed lower sensitivity in the detection. 77.1% of isolates were sensitive to Imipenem, 75% were sensitive to Aztronam, 68.8% were sensitive to Ciprofloxacin and 66.7% were sensitive to Gentamicin. Carpabenem remain the antibiotic of choice for managing of this infection.