الفهرس 
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Abstract
Summary and conclusions
This prospective cross sectional study was carried out at Hepatology and GastroenterologyDepartments of Benha University and Agouza police hospital during the period from April 2012 to September 2013.It was conducted upon (114) adult patients with HCV-related chronic liver diseases, their ages ranged from 22 to 60 years old and 76 (66.7%) of them were males.
• All patients were subjected to the following:-Thorough history taking, Complete clinical examination, laboratory investigations (FBS, CBC, ALT, AST, and S.billirubin, INR, ALP, S.albumin, P.T and serum creatinine) and virological studies (HCV-Ab, HBV-sAg and Quantitative PCR for HCV RNA) were performed in addition to abdominal ultra-sonography, ECG, Echocardiography and liver biopsy in all patients.
• All patients were stratified into two groups:-
- Group I (chronic hepatitis group): It included 50 patients with chronic hepatitis C .
- Group II (cirrhotic group): It included 64 patients with HCV-related liver cirrhosis .
• Males represented 66.7% of the studied cases with significantly higher age and BMI in the cirrhotic group than the chronic hepatitis group.
• Chronic hepatitis patients had significantly higher platelets count and Serum albumin level than cirrhotic patients. On the other hand, other liver profile(ALT, AST, S.billirubin, INR and ALP),serum creatinine and viral load were significantly lower in chronic hepatitis patients than cirrhotic patients.
• Cardiomyopathy was detected in 14 patients (12.3%) of all studied cases.
• EF% was significantly lower in cirrhotic patients(child class A, B&C) than those with chronic hepatitis while IVSD,LVPWD, LVDs and LVDd were significantly higher in cirrhotic patients(child class A, B&C) than chronic hepatitis patients.
• EF% was significantly lower in patients with child class B&C than those with child class A.
• EF% was lower in patients with F2&F3 than patients with F1 without significant difference while LVPWD and LVDs were higher in patients with F2&F3 than patients with F1 with significant difference.
So it was concluded that:
1- Cardiomyopathy was detected in 12.3% of HCV-related chronic liver diseases.
2- EF% was significantly reduced by increasing the severity of liver disease.
3- IVSD,LVPWD, LVDs and LVDd were significantly higher in cirrhotic patients than chronic hepatitis patients.
4- EF% and serum albumin were significantly lower in cardiomyopathic group than non-cardiomyopathic group while liver profile(total billirubin, ALT, AST, PT, INR), viral load, IVSD, LVPWD, LVDs and LVDd were significantly higher in cardiomyopathic group than the other one.