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Abstract High intake of total dietary fat is associated with increased risk for obesity,some types of cancer and possibly gallbladder disease. Epidemiologic and clinical studies provide strong and consistent evidence for the relationship between saturated fat intake, high blood cholesterol, and increased risk for coronary heart disease. A reduction of energy intake through a reduction of dietary fat intake by modifying the diets, however, successful reduction of fat consumption has not been fully achieved. The food industry, in response to consumer demands, has recently focused attention on the development of non fat, reduced fat, fat mimetics, and low calorie foods. Some of these fat substitutes are carbohydrates polyesters such as sucrose and glucose polyesters. The present study aims to synthesized same fat replacers by using some sugars such as glucose and sucrose and reacted with fatty acid methyl esters (FAME), study the physical properties of the products were compared with commercial soybean oil The biological studies of feeding sucrose polyesters as fat-replacer in the level of 5%, 10%, 15% on male albino rats treated. To achieve this aim the following procedures was carried out 1-Preparation of fatty acid methyl esters: Four methods were used for methylation fatty acids to obtained the high yields. 2- Glucose polyesters (GPE) and sucrose polyesters (SPE) were synthesized by interesterification of glucose, sucrose and long - chain fatty acid methyl esters (FAME) blends of mixture fatty acids under special condition. 3- The chemical structure of SPE and GPE were elucidate by infra-red (IR) and H1- nuclear magnetic resonance (H1- NMR) spectroscopy, Thin layer chromatography (TLC) and Gas chromatography (GC). 4- Physical properties of SPE and GPE were compared with commercial soybean oil.5- The biological studies of feeding sucrose polyesters as fatreplacer were carried out |