الفهرس 
Introduction and aim of workOnly 14 pages are availabe for public view
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Abstract
INTRODUCTION AND AIM OF WORK **
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Chronic liver disease is an important task that needs
various modes of investigations to determine the degree of
liver affection and sequalae of its long standing disorder.
Clinical and laboratoy tools have been used for long
times to assess liver cell function and disease progress.
With the development of Nuclear Medicine, functional images
are now obtainable by various radionuclides. These add to
the known liver functional tests and provide a new approach
towards the assessment of liver function.
Radio-labelled colloids can assess the reticulaendothelial
patency of the liver and spleen and the pattern
of tracer uptake and distribution between the two organs is
directly related to the efficacy of Kupffer cell population.
On the other hand, Technetium-99m labelled HIDA
compounds (hepatic imino diacetic acid) are employed to
assess the functional integrity of the hepato-biliary
system. Tc-99m HIDA compounds when injected intravenously,
are taken up by the hepatocytes, and then excreted in bile.
Sequential imaging allows to obtain functional images of the
various phases
Therefore, the
of tracer journey inside the
biokinetics of the injected tracer
body.
can be
followed and imaged. A normal scintigraphic pattern depends
on a healthy population of hepatocytes.
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