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Abstract Summary Cesarean section is considered the most common surgical procedure in the world. The number of operations performed annually worldwide is estimated by about one million cases. The type of anesthesia used and the way by which it is managed by are considered important elements in determining the outcome of cesarean section as both general and spinal anesthesia used in cesarean section have advantages and disadvantages, so there is no completely perfect way of anesthesia to perform. The most important factors that determine the type of anesthesia include; complications associated with pregnancy, parental choice, urgency of the operation, the experience of the anesthesiologist, medical history of the mother and the choice of the obstetrician. Some studies demonstrated that the amount of blood loss in women who receive spinal anesthesia in cesarean sections is less when compared to women who receive general anesthesia, as well as post-operative pain. Also the ability to move and walk in women who receive spinal anesthesia is faster than women who receive general anesthesia. Summary 106 However, these results should not be taken into consideration without further studies and researches to compare between spinal anesthesia and general anesthesia. Accordingly, the objective of conducting this research was to evaluate the use of both general and spinal anesthesia in cesarean section to determine which one was associated with less blood loss. This research was conducted on one hundred and fiftyfive pregnant women carrying single full term infant, between 25 and 35 years old, and did not undergo any previous operations in the lower abdomen except cesarean sections and did not have any bleeding tendency, then undergone a cesarean section after random distribution into the two studied groups, one with general anesthesia and one with spinal anesthesia. The first group who had undergone general anesthesia included seventy-seven pregnant women, while the second group who had undergone spinal anesthesia included seventy eight pregnant women. All circumstances were united in both groups regarding intravenous fluids and medications used; together with measuring of blood pressure and other vital data of the women. Basic data of the study has been recorded including: age, parity, hemoglobin and hematocrit before, and on third day after CS. Amount of blood loss has been calculated and recorded using Summary 107 the acute normovolemic hemodilution equation. Secondary outcomes has also been recorded including: vital signs, urine output, the number of fainting and headache attacks, need for blood transfusion and the elapsed time from the end of the operation till lactation ,mobilization , passing flatus and ability to eat and drink. The mothers were submitted to strict follow up until discharge from the hospital usually on the morning of third day. The results showed that the group which had a cesarean section under spinal anesthesia has a statistically significant 3rd day post-operative higher level of hemoglobin (P< 0.001), when compared with general anesthesia, with a mean difference of 0.660g/dL and also a statistically significant 3rd day postoperative hematocrit percentage higher with the spinal anesthesia group with a mean difference of 1.507% (P= 0.002). By applying of hemoglobin and hematocrit values in the acute normovolemic hemodilution equation, it was found that women operated under general anesthesia had more amount of blood loss than those operated under spinal anesthesia with a mean difference of 152.760 ml with the use of hemoglobin values and 174.274 ml with the use of hematocrit values. The results also showed that the spinal anesthesia group had a significant higher percentage in headache attacks versus Summary 108 general anesthesia group, lower percentage in blood transfusion post-operatively versus general anesthesia group, shorter time till breast feeding with a mean difference of 54.3 minutes, shorter time till start of ambulation with a mean difference of 69.36 minutes and longer time till first request for analgesia with a mean difference of 17.646 minutes. In this study, there were no statistically significant differences between both groups regarding post-operative; vital signs, urinary output, fainting attacks, time elapsed from the end of the operation till passing flatus and the ability to eat and drink. As a result of this research, it is recommended to use spinal anesthesia in cesarean deliveries for convenience and safety for the mother due to less bleeding and less postoperative pain. |