الفهرس 
Review of literatures
Material and MethodsOnly 14 pages are availabe for public view
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Abstract
First I am greatly indebted in my work and success to our merciful ”Allah” who gave me the ability to terminate this work Great appreciation, profound gratitude and deepest thanks are offered to Prof. Dr. Magdy Salah Mostafa Amer Prof. of pharmacology and vice -dean of Community Service and Environment Development Affairs. Fac.Vet. Med., Mansoura University for his kind supervision, unlimited help, valuable advice, encouragement, keen suggestion during the course of this study and revision all the details that enabled me to finish this work. He gave me a lot of his experience; devoted a lot of time and constructive criticism helped me to give this work.
Grateful thanks, deep-seated sincere appreciations are also extended to Prof. Dr. Mohammed Gabr Elsayed Gabr Prof. and head of pharmacology Dept. Fac. Vet. Med., Mansoura University for his help, cooperation and kind supervision, continuous guidance, unlimited help, valuable advice, encouragement, keen suggestion during the course of this study and revision all the details that enabled me to finish this work and under his stimulating supervision and criticism this work was achieved.
I would like to express my grateful thanks, very great indebtedness to Prof. Dr. Gehan Nabil Ahmed Gad Prof. of pharmacology, Animal health research institute, zagazig-for her kindness, generous attitude, continuous support, valuable advice, supervision and encouragement, awarding efforts to facilitate the difficulties during the course of this study and revision all the details that enabled me to finish this work .
Grateful thanks to Dr. Mohammed Fawzy lecturer of Pathology, Dep. Fac. Vet. Med., Mansoura University for his kind help in performing the histopathological study.
Finally my thanks to every hand help me to complete this work and to all members of Pharmacology Deptartement, Faculty of Vet. Med., Mansoura University for their help and cooperatio