الفهرس 
Staging of chronic Kidney DiseaseOnly 14 pages are availabe for public view
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Abstract
The immune defect in CRF and hemodialysis patients is associated with a monocytic dysfunction. The present study was designed to study CD14 and CD16 expression on monocytes in CRF patients during hemodialysis. The study was conducted on 50 patients with CRF, on regular HD. 15 healthy volunteers were included in the study to serve as controls. All cases were subjected to routine hemogram and kidney function tests. CD14 expression and CD14 CD16 coexpression on monocytes was determined by flowcytometry. The results obtained revealed non-significant decrease in total leucocyte count and absolute monocyte count in HD patients in comparison to controls. There was a near significant increase in the pro-inflammatory monocyte populations (CD14++ CD16+ and CD14+ CD16+) in the last third of dialysis session (~120 min) in HD patients than in healthy controls. This increase was near significantly positively correlated with CRP levels. This might refer to a degree of inflammation in HD patients.