Search In this Thesis
   Search In this Thesis  
العنوان
study of the serum amylin (fslet amyloid polypeptide) level in obese subjects
المؤلف
el-kholy, mohamed fathalla
هيئة الاعداد
باحث / محمد فتح الله الخولى
مشرف / مغازى على محجوب
مشرف / صلاح شلباية
مشرف / هالة محفوظ
مشرف / محمد رضا حلاوة
تاريخ النشر
1998
عدد الصفحات
185 ص.
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الغدد الصماء والسكري والأيض
تاريخ الإجازة
1/1/1998
مكان الإجازة
جامعة عين شمس - كلية الطب - غدد صماء
الفهرس
Only 14 pages are availabe for public view

from 185

from 185

Abstract

Amyl in (islet amylo1d polypeptide) IS 3 7 ammo
acid peptide hormone mainly produced by islet beta cells,
co-secreted with insulin. Actions of amylin is mainly
exerted on fuel metabolism as it antagonises actions of
insulin on skeletal muscles but not on adipose tissue so it
stimulates process of glycogenolysis and increase lactalc
turnover which acts as substrate for gluconeogensis in
liver inc.reasiug hepatic glucose oulput. So amylin induces
insulin resistance in skeletal muscles. Amylin inhibits
insuliu seen:\ iou.
Obesity is a very important risk factor 111
development of insulin resistance especially in patient
with type II diabetes.