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العنوان
The Pattern of Glucose Intolerance among Pregnant Women with Unexplained IUFD Attending Women’s Health
Hospital Assuit University – Egypt
/
المؤلف
Mostafa, Ahmed Mohamed.
هيئة الاعداد
باحث / احمد محمد مصطفى
مشرف / ماهر صلاح محمد
مناقش / حازم سعد الدين محمد
مناقش / كمال محمد زهران
الموضوع
Women- Diseases.
تاريخ النشر
2013.
عدد الصفحات
86 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
الناشر
تاريخ الإجازة
26/6/2014
مكان الإجازة
جامعة أسيوط - كلية الطب - Obstetrics and Gynecology
الفهرس
Only 14 pages are availabe for public view

from 95

from 95

Abstract

Intrauterine fetal death refers to babies with no signs of life in utero after 24 weeks. This is common, with 1 in 200 babies born dead. Overall, over one third of IUFD are small-for-gestational-age fetuses with half classified as being unexplained. Commonly associated antepartum conditions include congenital malformation, congenital fetal infection, antepartum haemorrhage, pre-eclampsia and maternal disease such as diabetes mellitus. For women with clinical diabetes, about 9.5% suffer from late IUFD.
Results:
It shows the demographic data of study group and control groups. There was no statistically significant difference between groups. It shows data about delivery in study and control groups there was no statistically significant difference between study and control groups regarding to the duration between admission and delivery, paratogram done in delivery process and mode of delivery (P > 0.05), but there was a statistically significant difference between study and control groups with medication given during delivery (P< 0.03) where most of women with IUFD received drugs for induction or augmentation of labour and appearance of the placenta (P < 0.001). Women with IUFD reported higher R.P.S than women in the control group, both this difference was statistically not significant (P > 0.05). HbA1c & Random blood sugar in study and control groups.
There is significance difference between study and control in HbA1c (P<0.05) and no significance difference with random blood sugar (P> 0.05). 68.09% of women had unexplained cause for their attributed to IUFD, 6.9% Hypertensive disease with pregnancy (Preeclampsia, eclampsia, chronic hypertension, Gestational hypertension), 5.5% for were accidental hemorrhage and 11.2% were small gestational age. women with unexplained IUFD showed tendency toward higher mean R.B.S level of more than 2 m mole. This difference was statistical significant , there was a statistical significant difference between both group as regard to parity, history of previous abortions and the mode of delivery with tendency toward low parity, more no of previous abortion and more women who achieve vaginal delivery in unexplained group. There was no statistical significant difference between both groups as regard to fetal weight, sex and mother age (P>0.05).
Women with unexplained IUFD who had elevated HbA1c level showed tendency towards older maternal age, prolonged labour duration, higher parity and more previous abortion. These differences were statistically significant. They also showed bigger fetal weight (more than 3000 gm), the women with normal of HbA1c level both this difference was statistical not significant. This may reflect that HbA1c does not always reflect poor diabetic control at the time of IUFD. The mean value of random blood glucose was 5.67 ± 1.81 in normal HbA1c vs. 6.45 ± 2.96 in elevated HbA1c with significance difference (P<0.05). Also 25% of patients in normal HbA1c elevated vs. 32.4% of patients in elevated HbA1c with significance difference (P<0.05). This significant difference seems logic because normal HbA1c is expected to be abnormal in women with uncontrolled diabetes and vise versa. However, these figures reflect that normal blood glucose, to some extent, does not mean normal HbA1c