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العنوان
Role Of Melatonin In The Protection From
Lenticular Damage Caused By UVB
Irradiation/
المؤلف
Mohamed ,Amira Ali.
هيئة الاعداد
مشرف / منى صلاح الدين حسن طلعت
مشرف / سلوى عبد القوى احمد
مشرف / ناهد صالح حسن
باحث / اميره على محمد غالب
الموضوع
Melatonin. Protection. UVB.
تاريخ النشر
2013.
عدد الصفحات
P.171:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الفيزياء الذرية والجزيئية ، وعلم البصريات
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة عين شمس - كلية العلوم - Physics
الفهرس
Only 14 pages are availabe for public view

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from 171

Abstract

Atmospheric changes such as depletion of ozone layer in the
stratosphere are believed to lead to rises the level of ultraviolet
radiation on the earth. In general, there are a number of body
components that absorb ultraviolet radiation and may induce
photochemical damage to the tissue. The most common are
chromophores, nucleic acid and proteins including various types of
enzymes. All these factors lead to opacity of the normal crystallin
lens that produces an impairment of vision and associated with
cataract formation.
This study aimed to investigate the damaging effect of total and
fractionated doses of ultraviolet B (UVB) radiation on the eye lens
and the effect of melatonin against oxidative stress in UVB radiationinduced
cataract development.
Twenty-five New Zealand male rabbits weighing 1.5-2 kg were
used in this study and divided into five groups (five rabbits each).
Group I. Rabbits kept as control without any treatment.
Group II. Rabbits received a total dose of 3.12 J/cm2 UVB and
they were left for one week.
Group III. Rabbits injected intraperitoneal with melatonin
(4mg/kg) daily for one week before exposure then they
received a total dose of 3.12 J/cm2 UVB and following the
exposure they again injected intraperitoneal with melatonin
daily for one week.