الفهرس 
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Abstract
Androgenetic alopecia (AGA), is the most common hair loss disorder affecting both men and women, and is characterized by progressive, patterned hair loss from the scalp. Genes and hormones are implicated in the pathophysiology of this hair type disorder. The clinical change in hair density, related to a change in the hair cycle and miniaturization of the hair follicle, is generally considered to be potentially reversible.Certainly, the pattern of hair loss is different in women and the prevalence is lower than that in men. It has been demonstrated that the dermal papilla is rich in androgen receptors and is the primary target of androgen action. Cells in genetically programmed hair follicles contain the enzyme 5α –reductase. This enzyme is found in higher quantities in the scalp follicles of affected men and women.FPHL may have described by diffuse thinning of the crown hair region with preservation of the frontal hairline, and there are two scales that describe this pattern: the commonly used 3-point Ludwig scale, and the 5-point Sinclair scale Female androgenetic alopecia of male pattern (FAGA.M) has described by Thinning and shortening of crown hair associated with bitemporal recession “Hamilton–Norwood type”, Hamilton considered that FAGA.M as diagnostic of women with circulating androgen levels similar to men and with a hyper sensibility of target follicular organ to androgens.There is a strong association between FAGA.M and polycystic ovary and other causes of hyperandrogenaemia Therefore, most women who present with FAGA.M as their primary complaint may have polycystic ovary and have indices of abnormal androgen production in the form of elevated testosterone, androstenedione, free androgen index (testosterone/ sex hormone binding globulin×100) and lower sex hormone binding globulin.High androgen levels in AGA patients, contribute to the development of atherosclerosis and thrombosis, and increase the tendency to hypertension and hypercholesterolemia. This may be due to the presence of androgen receptors in the arterial wall endothelium or to other unknown mechanism.The meaningful association of female androgenetic alopecia and coronary heart disease had been well documented, but few studies had been focused on the importance of lipid parameters in female patients with androgenetic alopecia.The aim of this study was to evaluate atherogenic index of plasma (AIP) and serum lipid levels in female AGA to investigate whether there is an association between female AGA and atherogenic index. Consequently, we aimed to assess could female AGA be considered a risk factor for cardiovascular disease or not.The current study included forty female patients suffering from AGA twenty female patients with FPHL, other twenty female patients with FAGA-M and twenty sex and age matched healthy controls. They were selected from the Outpatient Clinic of Dermatology and Venereology Department in Menoufiya University Hospital. Written consent forms approved by Committee of Human Rights in Research in Menoufiya University was obtained from every case and control subject.