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العنوان
Residues of oxytetracycline in rabbit tissues by using hplc /
المؤلف
Ibrahim, Ramy Mohamed Kamel.
هيئة الاعداد
باحث / Ramy Mohamed Kamel Ibrahim
مشرف / Sameh M. El-Nabtity
مشرف / Mohamed A. Kamel
مشرف / Mohamed A. Kamel
الموضوع
Veterinary Pharmacology. Rabbits. Oxytetracycline.
تاريخ النشر
2014.
عدد الصفحات
103 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة الزقازيق - كلية الطب البيطرى - department of Pharmacology
الفهرس
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Abstract

Drug residues of oxytetracycline L.A. in rabbit (kidneys, liver and breast muscle) was determined using high performance liquid chromatography (HPLC) after single intramuscular administration of drug at a dosage of 20 mg/kg b.wt.
from this study, we need to know the withdrawal time of oxytetracycline LA (Alamycin LA®) from (kidneys, liver and breast muscle) of rabbit after single intramuscular administration of drug at a dosage of 20 mg/kg b.wt and therefore when rabbitsʹ organs (kidneys, liver, breast muscle) become safe for human consumption.
Experimental design
 Thirty clinically healthy Newzeland rabbits weighting 2-2.5 kg and 2 months of age were obtained from Farm of faculty of Veterinary Medicine, Zagazig University.
 The rabbits were housed in batteries in post graduate research laboratory in Faculty of Veterinary Medicine, Zagazig University and fed balanced ration with free access to water.
 Rabbits were injected with oxytetracycline LA (Alamycin LA® ) by a dosage of (20 mg/kg b.wt) by deep I/M and slaughtered at 1st ,3rd ,5th , 7th ,14th ,21st ,28th ,30th ,32nd days post injection (3 rabbits at each) and 3 rabbits kept as a control.