Search In this Thesis
   Search In this Thesis  
العنوان
Synthesis and biological evaluation of some novel fused pyridine and pyrimidine derivatives and related glycosides /
المؤلف
Afify, Amina Alsoudy Abd-Elgwaad.
هيئة الاعداد
باحث / أمينة السعودى عبدالجواد عفيفى
مشرف / عادل عبدالهادى نصار
مشرف / عمر عبدالفتاح محمد عبدالله
مشرف / ناجى محمود خليفة
الموضوع
Coenzymes. Nucleotides. Oxidoreductases.
تاريخ النشر
2014.
عدد الصفحات
120 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
الناشر
تاريخ الإجازة
19/2/2014
مكان الإجازة
جامعة المنوفية - كلية العلوم - الكيمياء
الفهرس
Only 14 pages are availabe for public view

from 120

from 120

Abstract

Treatment of ethyl cyano hydrazide with arylidine malononitrile give amino pyridine.The latter react with different aldhydes,acids give 1,2,4-
triazolopyridine.
Also amino pyridine were allowed to react with different sugars afforded
different glycosides.
While reaction of arylidine malononitrile with thiourea in presence of
ethanol and K2CO3 at reflux temperature afforded amino-5-
isocyanothiopyrimidine.
Amino -5-isocyanopyrimidine react with HCl in presence of ACOH or
Formamide give fused pyrimidine derivatives.
The synthesized compounds were tested for their biological activity as
anti-bacterial and antiviral activity.