الفهرس 
Chronic Non Cholestatic Liver Diseases in ChildrenOnly 14 pages are availabe for public view
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Abstract
Children with chronic liver disease are at risk for
developing vitamin K deficiency because of inadequate dietary
intake.
This study was conducted on 25 infants, children and
adolescents, suffering from chronic non cholestaic liver disease
(15males and 10females). They age ranging from 1.5 to 16
years.
All were subjected to thorough medical history taking
with special emphasis on hepatic symptoms and bleeding
tendency symptoms, full clinical examination, investigations
for liver functions, and measurement of serum PIVKA II levels.
Assessment of liver diseases severity was done and patients
were categorized according to The Child-Pugh classification to
Child A, B, C.
Then collected data were reviewed, coded, and entered
PC where statistical analysis was done using SPSS (statistical
package for social science) which revealed that:
PIVKA II levels were elevated in all patients with
chronic non cholestatic liver disease. There was a significant positive correlation between
PIVKA II and melena, ascites, lower limb edema and
haematemesis.
There was a significant positive correlation between
PIVKA II and PT, INR.
There was a significant negative correlation between
PIVKA II and PLT.
PIVKA II was not correlated to Child’s classification