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Abstract This work was carried out on 22 male cigarette smokers with normal resting pulmonary function tests (after exclusion of cardiac and pulmonary diseases) to evaluate their exercise performance and post-exercise pulmonary functions. Patients were classified according to smoking index (pack/years index) into: • Mild smokers (smoking index <10). • Moderate smokers (smoking index 10 - 20). • Heavy smokers (smoking index >20). Each patient underwent the following: Full history taking, clinical examination, routine laboratory investigations, ECG and echocardiography, chest X ray (postero-anterior) and lateral views, resting pulmonary functions (FEV1, FEV1/FVC, PEF, FEF25-75% and MVV were measured), cardiopulmonary exercise testing (VO2 max was measured) then post exercise pulmonary functions were done. This study showed that there was a statistically significant difference between the three groups regarding resting pulmonary functions (there was a significant difference between groups I & III for all pulmonary functions and groups II & III regarding FEV1, FEV1/FVC &FEF25-75). Also the results showed that there was a statistically significant difference between the three groups regarding pulmonary function tests after exercise (there was a significant difference between groups I & III for all pulmonary functions, groups I & II regarding FEF25-75% & MVV and groups II & III regarding FEV1, FEV1/FVC, PEF & FEF25-75%). Also there was a significant difference between the three groups regarding VO2 max and there was a statistically significant +ve correlation between VO2 max and FEV1 before and after exercise & between VO2 max and FEF25-75% after exercise in group II. In group III there was a statistically significant +ve correlation between VO2 max and FEV1, FEV1/FVC before and after exercise & between VO2 max and both MVV & FEF25-75% after exercise. These results emphasize the effect of cigarette smoking on pulmonary functions and exercise performance. |