الفهرس 
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Abstract
The eye appears to be the target organ that presents with the most commonly recognized signs and symptoms of allergy. The sensitization process begins with a potential allergen coming into contact with antigen-presenting cells on the ocular surface. This initial step induces a series of intracellular communications resulting in the production of allergen-specific IgE, which binds strongly to the surface of ocular mast cells.
Adequate history and strong clinical suspicion are needed for the diagnosis of ocular allergic conditions. Beyond the key symptom of itching, presenting signs include conjunctival redness, tearing, chemosis, and eyelid swelling.
The aim of the present work was to identify the role of skin test in detecting the most common aeroallergens contributing in the pathogenesis of allergic conjunctivitis between the Egyptian patients.
Our study included one hundred patients, diagnosed to have allergic conjunctivitis with no other allergic disease.
All the selected patients were subjected to the following:
▪ Full history taking ,a thorough clinical and ophthalmological examination.
▪ Skin prick test using the most common aeroallergens.
▪ Serum total IgE using a sandwich enzyme-linked immunosorbent assay (ELISA) .
▪ Routine investigations including liver function tests, kidney function tests and blood glucose level.
▪ Complete blood count including eosinophil count.
In our study, we found that the skin prick test gave positive results in 34%of patients with allergic conjunctivitis. Most common aeroallergens were Mix.Mites and Mix.Pollens then Grasses. Indoor allergens were more prevalent among the PAC, while outdoor allergens were more prevalent among SAC and VKC.
Most of the patients with allergic conjunctivitis had high total IgE values, with significant difference between the three types ;SAC,PAC and VKC. We found a positive relation between eosinophilia and both skin prick test and total IgE values. Also we found a positive relation between skin prick test and total IgE level.