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Abstract The present investigations ”ere ,”’” ’p £l’formed on fifty farm of about 250,000 chickens farm may 1989 to may 1991 in Kaluobia Province. The incidence of the respiratory affection due to bacterial and fungal agents represented by 14.62%. These agents ”ere E. coli (3.7%), Haemophilus spp , (4%), Pasteurella spp , (0.82%), Salmonella spp . (2.5%) and Aspergillus spp. (3.6%). The trachea sho”ed congestion ”ith the presence of grayish spots on their mucosa and catarrhal tracheaitis. Congestion of the lungs, grayish ”hite foci and opaque of air sacs ”ere the most common gross findings in case of E. coli infection. The trachea show i ng congestion of its blood vessels with the presence of f ew eosinophilic debris in their lumen. The histopathological examination showed congestion and thrombosis of the pulmonary blood vessels, edema of their Halls and endothelial cells prolifration. The bronchi showed desquamation of their lining epithelium, .yperplasia, Focal leucocytic aggregation with interatrial tdema. Multiple areas of necrosis of the lung tissues were also seen. The most co” gross findings. in case of infectious coryza were was ’re4ema of the face. The lungs were congested. The t,t.cheal mucosa showed turbid fluid and petechae. The air sacs were opaque microscopically catarrhal rhinitis and sinusitis were seen. The trachea showed desquamation of its epithelial lining. The glandular epithelium showed hyperplasia and leucocytic infiltration. The lungs were congested with the presence of perivascular edema. The air sacs were thickened and edematous. The macroscopical findings in case of pasteurella infection were petechae of the trachea, grayish-white foci on the lung tissues. The air sacs showed cloudness. Microscopically, the tracheal mucosa membrane was congested. Eosinophilic debris in the atrii and inside the bronchial lumina were seen. Focal heterophilic aggregation in the lung tissues, perivascular haemorrhage, and leucocytic mainly lymphocytes were detected. The gross findings in case of Salmonella spp , were nodules of variable sizes situated in the lung tissues. The tracheas showed the presence of exudate in their lumina. Microscopically, the trachea showed degenerative changes in tracheal glands. Nodules in the lung tissues formed from caseated centeT surrounded with leucocytic aggregation mainly heterophil.. lymphocytes, macrophages and plasma cells were evideat •• Thickening of interatrial septa with leucocytic infiltr~ion were also seen. The bronchi showed leucocytic infil~~tion in the lamina propria. The air sa~s show~d leucoe~ic infiltration. Grossly the infected chickens with Aspergillus spp. revealed grayish to greenish pathces of few mm in diameter. On cutting surface, grassy material oozed. The nodules of few mm in diameter were also seen in lung tissues. The air sacs were opaque. Nicroscopically, the lamina propria of trachea showed leucocytic infiltration mainly mononuclear cells. Nodules formed from caseated material mixed with heterophils and lymphocytes ”ere evident. in the lungs. The fungal hyphae ”ere located peripherally which taken postive reaction with PAS. Focal leucocytic aggregation with interatrial edema also detected. The bronchi showing desquamation of the lining epithelium ”ith the presence of eosinophilic debris in the lumina. |