الفهرس 
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Abstract
Periodontitis is a chronic infectious disease characterized by the inflammation of the periodontal supporting tissues, resulting in loss of attachment and alveolar bone resorption. If left untreated, the disease continues with progressive bone destruction, leading to tooth mobility and subsequent tooth loss. The primary etiological agents are Gram-negative anaerobic bacteria arranged in a bacterial biofilm.
Ozone is a highly energetic form of oxygen, which has been used in human health since 1860.Topical application of ozone in management of gingivitis and periodontitis was investigated in a limited number of in vivo studies. However, there is no reliable data regarding the use of plant extracts as a vehicle for delivery of ozone to periodontal tissues.
This stimulated the idea of the present work in studying the effect of topical application of ozonated olive oil-gel as an adjunct to scaling and root planing (SRP) in treatment of chronic and aggressive periodontitis.
Twenty-five systemically healthy patients suffering from periodontitis were selected. All the selected patients have at least two contralateral posterior pockets with probing pocket depth of 4-6 mm in depth and loss in clinical attachment level ≥2mm.The patients were divided into two groups according to their periodontal status; group I included ten aggressive periodontitis patients and group II included fifteen chronic periodontitis patients.
Each group was further divided into two subgroups in a split mouth design according to the treatment received. Groups (I a) and (II a) were treated by SRP alone while groups (I b) and (II b) were treated by both SRP and topical ozone application. Topical application of ozonated olive gel was done once weekly for 4 weeks period.
Follow-up was done on basis of changes in both clinical parameters (PI, PBI, PPD & CAL) and bacteriological counts (total anaerobic and Porphyrmonas gingivalis count) as observed at 4 weeks and 8 weeks of the beginning of the study.
The results of the study revealed that topical application of ozonated olive gel as an adjunct to SRP resulted in statistically significant better improvement in clinical parameters. In addition, topical application of ozonated olive gel resulted in statistically significant higher percentage of decrease in total anaerobic load and P.gingivalis count both immediately after application and through the whole period of the study as compared to SRP alone. The results also showed that ozonated olive gel has an immediate antibacterial activity.