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Abstract Psoriasis is one of the most common clinical dermatological conditions. It is important to recognize that psoriasis is a term that includes a spectrum of disease ranging from localized plaques to more severe generalized involvement, with or without PsA and the associated manifestations of other autoimmune diseases. PsA is a common autoimmune inflammatory condition affecting the joints and entheses of patients with psoriasis. While the prevalence of arthritis in the general population is estimated at 2-3%, in patients with psoriasis it varies from 7 to 42%. Although arthritis usually develops in a setting of an established diagnosis of psoriasis, some patients may be unaware that they have psoriasis, or psoriasis may develop after the onset of arthritis. The present study was conducted on 100 patients suffering from psoriasis they were divided according to the presence or absence of rheumatic manifestations: (42) patients with no rheumatic manifestations, (40) patients with PsA diagnosed according to CASPAR criteria of diagnosis of PsA and (18) patients with other rheumatic manifestations. All patients were subjected to the following: 7) Full medical history taking 8) Clinical examination d. General examination e. Locomotor examination f. Dermatological examination 9) Laboratory investigation e. Estimated Sedimentation Rate (by Westergren method) f. Complete Blood Count g. Rheumatoid Factor (by Rose Waaler method) h. C-Reactive Protein 10) Radiological investigation d. Plain x-ray both hands e. Plain x-ray of pelvis and sacroiliac joint f. Plain x-ray of both feet 11) Disease assessment c. PASI score for psoriasis severity d. Moll and Wright criteria for PsA type 12) Statistical analysis of the data |