الفهرس 
Clinical problems and comorbidities with cerebral palsyOnly 14 pages are availabe for public view
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Abstract
Cerebral palsy (CP) is a group of non-progressive disorders of
motion and posture. It results from injury to the developing brain
during the antenatal, perinatal or postnatal period. Clinical
manifestations are related to the area of central nervous system
(CNS) affected. The clinical picture may vary considerably, from
high functioning mild monoplegia with normal intellect to severe
spastic quadriplegia with mental retardation.
Understanding the disease etiology, clinical manifestations and
management will help improve perioperative care of patients with
Cerebral Palsy
AETIOLOGY
Recognised risk factors for developing CP include: perinatal
hpoxia, prenatal infection, congenital abnormalities, trauma, and
genetic predisposition. CP is likely the final common endpoint
from a number of factors affecting early cerebral development,
rather than any one specific event. In premature infants, CP is
commonly a result of periventricular hemorrhages. For infants
born after 34 weeks gestation approximately 50% of spastic
quadriplegia CP is caused by prenatal problems including brain
maldevelopment, stroke, infections (toxoplasmosis, rubella,
cytomegalovirus, herpes virus i.e. TORCH) or genetic disorders.
Intrapartum hypoxia (birth asphyxia) for term infants is now believed to cause only 6% of CP. This is less common than
previously thought. Postnatal causes include meningitis, viral
encephalitis, hydrocephalus, trauma, surgical lesions and their
treatment.