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العنوان
Sufficiency of Vitamin D among Egyptian Females in Child Bearing Period\
الناشر
Ain Shams university.
المؤلف
Mattar,Marium Raouf.
هيئة الاعداد
مشرف / Matta Makram Anis
مشرف / Inas Mohammed Sabry
مشرف / Raef Malak Botros
باحث / Marium Raouf Mattar
الموضوع
Vitamin D. Egyptian Females. Child Bearing Period.
تاريخ النشر
2011
عدد الصفحات
p.:145
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الغدد الصماء والسكري والأيض
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة عين شمس - كلية الطب - Endocrinology
الفهرس
Only 14 pages are availabe for public view

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from 134

Abstract

Vitamin D plays an essential role in calcium homeostasis and bone metabolism. Recent evidence suggests that vitamin D may also be important for a variety of non skeletal outcomes including neuromuscular function, immunomodulation, and control of other hormonal system.
It is well known that exposure of the skin to direct sunlight is the most important source of Vitamin D, so that according to many causes like fear of skin cancer, traditional clothing and spending most of the time indoors many Egyptian Females are exposed to vitamin D deficiency.
The aim of this work was to evaluate the magnitude of Vitamin D deficiency/ sufficiency in a sample of Egyptian females in childbearing age.
Our study was conducted on 86 female subjects in child bearing age (16-50 years) randomly selected from outpatient clinic of Ain Shams University and their healthy relatives. We excluded chronic liver and kidney diseases, Diabetes Mellitus, Ischemic heart diseases, cancers, pregnancy and lactation.
For all subjects the following was performed:
1. History taking with special emphasis on dietary habits, social status, housing condition, sun exposure, type of clothes( Modern western or Traditional Conservative) and parity.
2. Physical examination including anthropometric measures, pulse, blood pressure, and presence of any skeletal deformities.
3. The following laboratory tests were performed:
• 25(OH) D by radioimmunoassay
• Parathyroid hormone by Elisa
• Serum calcium.
• Serum Phosphorus.
• Serum alkaline phosphatase.
• Serum Creatinine.
• Hemoglobin.
Results:
Our study showed high incidence of vitamin D deficiency among Egyptian females between the age of 16 to 50 years old as 70 subjects (81.4% ) have vitamin D deficiency (< 15 ng/ml, < 37.5 nmol/l), 8 subjects (9.3%) have relative insufficiency (15-29 ng/ml, 37.5-72.5 nmol/l), and the other 8 subjects have vitamin D sufficiency (≥ 30 ng/ml, ≥ 75nmol/l), Sun exposure and Vitamin D supplementation are the most important factors for normal Vitamin D level, while high parity inversely affect level of vitamin D when increased lead to decreased vitamin D.
On studying the correlation of 25(OH) D and other factors that may affect its level in blood, there was a high significant positive correlation between 25(OH) D and duration of sun exposure. In addition, there was a significant positive correlation between 25(OH) D and supplementation.
There was a significant negative correlation between 25(OH) D and Parity.
Conclusion:
Our study showed high prevalence of vitamin D deficiency among Egyptian females in childbearing age and there was positive correlation between vitamin D and sun exposure and supplementation and negative correlation between parity and Vitamin D.