الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
If individual segments are removed from bowel continuity and used for urinary diversion, the resorption area of the used bowel segment is lost to the physiological function of the gastrointestinal tract. Furthermore, the bowel segment retains its absorbing and secreting characteristics even after incorporation into the urinary tract. (16, 17)
This may result in changes to the absorption of food components such as vitamin B12 and reabsorption of bile acids in the small bowel and large bowel. Each bowel segment has particular, specific characteristics from which the typical metabolic consequences result. The extent of metabolic problems depends on the length and type of bowel segments used as well as on atrophy of the bowel mucosa subsequent to chronic urinary diversion, a patient’s renal and liver function and age. (16)
Table 1 Metabolic Complications of Urinary Diversions
Bone Disease:
• Demineralization
• Rickets (children)
• Osteomalacia (adults)
Hepatobiliary:
• Ammoniagenic coma
• Altered drug metabolism
• Cholelithiasis
Infection:
• Urinary tract infection
• Sepsis
Malignancy:
• Adenocarcinoma
• Transitional cell carcinoma
• Signet cell carcinoma
• Adenomatous polyps
• Sarcoma
• Undifferentiated carcinoma
Neurological
• Altered sensorium
• Peripheral neuropathy
Bowel dysfunction , Vitamin B 12 deficiency
Renal
• Hyperchloremic metabolic acidosis
• Hypokalemia
• Hypocalcemia
• Hypomagensemia
• Metabolic acidosis
• Nephrolithiasis
The aim of our study is to evaluate the early metabolic and electrolytes changes occurring in urine during storage in the ileum for one hour using direct model.
The study was conducted on twenty patients; Seventeen of them were male (85%) and three were female (15%). All the patients aged from 45 – 65 years.
All the patients were subjected to collection of 120 ml of patient’s urine intra-operatively; 20 ml used as control and other One hundred ml is instilled into 40 cm of ileal intestinal segment became be used for reconstruction of neobladder after the segment is compressed gently to move out its contents and then the segment is occluded on both ends by non crushing intestinal clamps. This one hundred ml of urine was kept inside ileal segment for one hour during cystectomy then the urine was be recollected to perform the following measures on this sample and the control sample: Na, K, Urea, Creatinine, PH, Specific gravity, Urine volume, Osmolality, Ca, P and Mg levels.
According to our results, there was a statistically significant increase level of Na, Ca, P, Mg and PH while decrease in Urea, Creatinine, K, Urine volume and Specific gravity after retention for one hour in ileal neobladder.