الفهرس 
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Abstract
Several species of the yeast genus Candida are capable of causing candidiasis. ey are members of the normal flora of the skin, mucous membranes and gastrootestinal tract. Candida species colonize the mucosal surfaces of all humans during or on after birth and the risk of endogenous infection is ever present. The major thogenic species are C. albicans, C. glabrata, C. krusei, C. kefyr, C. guilliermondii, parapsilosis, C. tropicaiis and C. lusitaniae. Candida species can affect genital ct, intestinal tract and oral cavity, but these thesis will stress on RVVC.
Recurrent vulvovaginal candidiasis, which is defined as three or more episodes r annum There are two forms of RVVC. primary RVVC which is idiopathic with t known predisposing factors, such as those identified for acute vulvovaginal
didiasis (AVVC) and secondary RVVC that is the occurrence of frequent pisodes of A VVC due to certain predisposing factors, predisposing factors include iIIlffiunosuppressive, antibiotic, cytotoxic therapies, the presence of intravenous .atheters and indwelling devices, very low birth weight, AIDS, diabetes, drug abuse lIld pregnancy.
Immune response to the fungal attack remam largely unknown. There is mbstantial agreement that local rather than systemic immunity plays a critical role, ~is was supported by some early clinical evidence as women with RVVC were not lUsceptible to other forms of superficial candidiasis as oropharyngeal and esophageal. Another was the emergence of clinical studies in women with HIV infection that were showed that although oral candidiasis was extremely common as immunosuppression progressed, vaginal candidiasis was no more common than in the nealthy population.