الفهرس 
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Abstract
The prophylactic use of antibiotics in many obstetric-gynecologic procedures, particularly cesarean delivery, is well established in clinical practice. Short-course antibiotic prophylaxis in women undergoing cesarean delivery reduces both endometritis and wound infections.
Routine prophylaxis is controversial for elective cesarean delivery. Even low-risk cesarean deliveries carry an appreciable risk therefore the role of antibiotic prophylaxis in elective cesarean delivery was thoroughly investigated and there is a large body of literature supports the prophylactic use of antibiotics in elective cesarean delivery.
In the extensive body of literature on cefazolin use for decreasing postoperative infection among patients undergoing elective cesarean delivery, a huge number of different antibiotics have been studied. choice should therefore be based on such other factors as cost and the wound site and expected flora and pathogens.
This study was conducted in the Department of Obstetrics, Qwesina Central Hospital during the period from June 2011 through to September 2012. The study included a total of 100 women who underwent elective cesarean section. Participants were randomly chosen equally divided in their number into 2 groups (each group 50 women) according to the regimen (preoperative or immediately after cord clamping) of prophylactic antibiotic used (Cefazolin).
The antibiotic regimens were as follow Group A: were received cefazolin (zinol®, Pharco, Egypt) 2 gm. IV. (15-30 minutes) preoperative.
Group B: were received cefazolin (zinol®, Pharco, Egypt) 2 gm. IV at cord clamping An informed written consent was taken from every woman participating in the study.
Follow up of the patient as long as she is hospitalized & discharged after confirmed positive intestinal motility & passage of flatus.
One week after discharge and at the day of removing sutures, patients were examined for wound and uterine infections.
Diagnosis of postoperative wound infection known by local tenderness, erythema, induration, fluctuation and pus discharge confirmed by swab culture for positive cases.
Diagnosis of urinary tract infection was by dysurea, frequency confirmed by complete urine analysis and urine culture for positive cases.
The findings of this study show that intravenous injection of cefazolin before skin incision and at the time of clamping the umbilical cord makes no significant difference in incidence of maternal infectious postoperative complications.
There was no significant difference in infection rate whether cefazolin were given before skin incision or at cord clamping.