![]() | Only 14 pages are availabe for public view |
Abstract Although the regimens of chemotherapy improved, about 30 - 35% of osteosarcoma patients however still had local or systemic relapse. The lung, involved in more than 80% of all patients. Surgical remission is critical in the management of these challenging patients. Local control was achieved by amputation or by local excision. Treatment at disease recurrence should consist not only of local control with surgery but also systemic treatment, however, the difficulty lies in the number of effective agents of chemotherapy that remain available to these patients. Only 25% of patients are expected to survive 5 years after recurrence and 10-year survival is approximately 20%. . Keywords: osteosarcoma, relapse, treatment, chemotherapy, surgery, prognosis. |