الفهرس 
ACKNOWLEDEGEMENTOnly 14 pages are availabe for public view
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Abstract
Odontogenic keratocyst (OKC) deserve special consideration because of its specific histological feature and clinical behavior. Matrix metalloproteinase-2 (MMP-2) is a gelatinase form of the MMPs family, which is a group of proteolytic enzymes that degrade many types of collagen. Our purpose of this study is to evaluate and compare the biological behavior of the OKC using MMP-2 versus dentigerous cysts (DC), radicular cysts (RC) and ameloblastoma (AMB). Sixty specimens including OKC tissues (n=26), DCs (n=10), RC (n=14) and ameloblastoma (n=10) were examined for MMP-2 expression using avidin biotin complex methods. Statistically, AMB showed the highly significant mean area percentage for MMP-2 expression followed by the OKC. However, the DC and RC showed the lowest significant mean area percentage. MMP-2 protein may be one of the factors enhancing invasion of OKC and ameloblastoma that reinforcing the OKC classification as an odontogenic tumor.