الفهرس 
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Abstract
The aim of the present study was to assess the extent and severity of coronary artery disease in diabetic patients and to look for risk factors of atherosclerotic burden of coronary artery among diabetics.
This study was carried out on fifty patients admitted at Alexandria main university hospital with type 2 diabetes mellitus who underwent coronary angiography because of clinical indication to coronary angiography. The diagnosis of diabetes was based on the American Diabetes Association (ADA) criteria.(186)
All patients were subjected to full history taking, Complete Clinical Evaluation: (including fundus examination and neurological examination), Laboratory investigations including glycaemic state,lipid profile,renal function,inflammatory markers (hs CRP, fibrinogen) and urine analysis for evedince of micro¯o albuminurea,ECG, transthoracic echocardiography and coronary angiography. The location and extent of coronary artery occlusions were assessed using Cumulative Coronary Stenosis Score.(194)
Several trials have evaluated the prediction of extent of coronary artery disease in diabetic patients. However, much remain to be learned to explain and to look for the risk factors in diabetics associated with severity and extent of coronary artery disease.
In our study males were presented by 54% and females 46% of studied group, and there were no statistical significant differences between gender regarding coronary score .
Also patients with grade I, II and III hypertension were 38%, 28% and 12% respectively with amen of SBP 147±6 , 169±17 and 184±4 and a mean of DBP 93±3 ,104±3 and 112±3 respectively, there were no statistical significant differences between them and normotensive patients regarding coronary score.
In the present study current smokers were presented by 46% of studied patients , however there were no statistical significant differences between them and non smokers regarding coronary score.
The study showed that FBS , PPBS and HbA1c was ranged between 90-322, 121-420 and 5.3-13.8 with a mean of 181±66.46 ,256.6±82.67 and 9.41±0.94 respectively, there were not significantly different in the patients with controlling blood glucose and not regarding coronary score compared to those with normal of these three parameters and were not related to CAD severity in correlated analysis. However, HbA1c did not add somewhat to the prediction of coronary score in the analysis.
Furthermore, the patients who having different grades of neuropathy were 31 patients,with most patients in grade 1,we observed that there were highly statistical significant differences between this group of patients and highly coronary score ( p value 0.037).Also patients who having different grades of retinopathy were 26 patients with most patients in grade III also there were highly statistical significant differences between this group of patients and highly coronary score ( p value 0.002).
An evidence of microalbuminuria were present in 56% of patients and patients with frank proteinuria were 8% with a mean of 3.993±2.0118 and 5.188±3.0051 respectively.