الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Public concern about possible increases in childhood cancer incidence in Egypt led us to examine recent childhood cancer trends. Methods: Cancers diagnosed in 3483children under age 18 years from 2002 to 2006 and reported to registries in the National Cancer were investigated. Cancer trends were analyzed according to anatomic site and histologic categories of the International Classification of Childhood Cancer. Results: A modest rise in the incidence of leukemia, the most common childhood cancer. For brain and other central nervous system (CNS) cancers, incidence rose strikingly. A few rare childhood cancers demonstrated upward trends (e.g. adrenal neuroblastomas, and retinoblastomas). In contrast, incidence decreased modestly for lymphomas). Conclusion: There was a substantial change in incidence for the major pediatric cancers, and rates have risen relatively in comparison with the previous NCI study. The strikingly apparent increase that was observed for brain/CNS cancers suggest that the increases likely reflected diagnostic improvements or reporting changes as well as establishment of tremendous radiotherapeutic treatment. Recommendation: a national cancer registry is required to better determine the real magnitude of childhood cancer in Egypt and thus leading to better management. |