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العنوان
“Stereotactic radiosurgery in management of pediatric arteriovenous malformations”
A systematic review of literature and meta-analysis
المؤلف
AMIN,ABDELRAHMAN AHMED RAGAE ,
هيئة الاعداد
باحث / ABDELRAHMAN AHMED RAGAE AMIN
مشرف / HOSSAM MOHAMED EL- HUSSENI
مشرف / AYMAN ABDEL RAOUF EL SHAZLY
مشرف / AHMAD EL-SAYED DESOKEY
الموضوع
Arteriovenous malformations
تاريخ النشر
2012
عدد الصفحات
146.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة عين شمس - كلية الطب - neurosurgery
الفهرس
Only 14 pages are availabe for public view

from 146

from 146

Abstract

Arteriovenous malformations are congenital lesions arising from abnormal blood vessels formation. It represents the most common cause of intracranial hemorrhage in the pediatric age group.
Aiming for its removal or complete obliteration, surgical approaches and endovascular embolization were used. But being invasive, harbour highly potential devastating morbidities and mortality. Since the emerge of stereotactic radiosurgery, being such a minimally invasive modality, significant consideration for its usage in management of pediatric arteriovenous malformations has evolved.
In an attempt to clarify the effectiveness and safety of stereotactic radiosurgery in management of arteriovenous malformations, we conducted this study. This systematic review and meta-analysis of 14 studies reporting management of pediatric arteriovenous malformations with stereotactic radiosurgery done through the last 12 years providing data and analysis for 1092 patients between the age of 2 and 18 years that have been treated in different centers and institutes all over the world since 1984.
This study results revealed that stereotactic radiosurgery in management of pediatric arteriovenous malformations does have a high overall obliteration rate with low morbidity and mortality rates.
Stereotactic radiosurgery is an effective and safe modality in management of arteriovenous malformations in the pediatric age group.
Guided by the results of our study, it is recommended that stereotactic radiosurgery is to be used either exclusively or in combination as a primary or an adjuvant modality in multi-modality management protocols, but yet emphasizing that the management protocol must be tailored for each patient separately according to different characteristic features and factors.