الفهرس 
Aim of workOnly 14 pages are availabe for public view
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Abstract
SUMMARY
Obesity has became one of the most important causes of heart diseases, cancer and other diseases that increase the incidence of premature death in recent years and during the last ten years, the increase consumption of sugars in diet and lack of daily physical activities due to reliance on modern technology have became the most dangerous risk factors that leads to development of obesity and its hazards.
By studying the effect of overconsumption of sugar in diets on different experimental animals, we found a strong relationship between overconsumption of sugar and obesity.
Sucrose or cane sugar plays an important role in supplying energy necessary for body functions. It breaks down in small intestine to glucose and fructose by sucrase enzyme and both of them are absorbed where fructose is converted to glucose in liver and glucose used by every cell in the body in production of energy. With overconsumption of sucrose much of glucose produced not burned but converted stored in the body in the form of fat leading to obesity.
Physical activity play an important role in equalizing energy intake and energy expenditure in human body by burning extra energy gained to the body and thus prevent its storage in the body as fat so low physical activity is associated with obesity.
This study is done to detect the possible effect of regular physical activity on high-sucrose diet-induced obesity and its relation to the levels of lipids in the blood.
Adult white male albino rats are used which were divided into 3 main groups:
Group I: control group
Receive standard diet and remain untrained for 4 weeks.
Group II: high sucrose group subdivided to:
Group IIa: receive sucrose 30% and remain untrained for 4 weeks.
Group IIb: receive sucrose 50% and remain untrained for 4 weeks.
Group III: exercise group subdivided to:
Group IIIa: receive sucrose 30% and perform exercise for the last 3weeks of the experment (45min/day) in tanks.
Group IIIb: receive sucrose 50% and perform exercise for the last 3weeks of the experment (45min/day) in tanks.
Obesity was assesed by measuring body mass index (BMI) which equall weight of rat in grams/ length of rat in Cm2, also blood glucose and lipid profile levels are measured. All the previous parameters are used also to asses the effects of regular exercise.
The obtained results of this study could be summarized as follow:
• Consumption of high surose diet in which sucrose represent 30% and 50% of caloric requirement causes a significant increase in body weight manifested by increase BMI serum glucose and lipid profile when compared with control group.
• Regular exercise results in significant decrease in BMI, serum glucose and lipid profile in exercise group when copmared with high sucrose group
RECOMMENDATIONS
• High sucrose consumption is a risk factor for obesity and other diseases so further studies needed to detect the effects of feeding sucrose in concentrations > 50% on liver enzymes, insulin level, serum oxidative stress enzymes and parenchyma of some organs.
• Regular physical exercise is protective against high sugar-induced obesity but further studies needed to detect the effects of regular exercise on fatty liver induced by overconsumption of sucrose.
• Further studies needed to study organ uptake of glucose during high consumption of sucrose.
• Further studies needed to detect expression of genes due to overconsumption of sucrose.