الفهرس 
Alzheimer’s diseaseOnly 14 pages are availabe for public view
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Abstract
The fundamental goal of the present study is to evaluate the possible therapeutic role of different hormones estrogen, melatonin or DIII’:;\ in alleviating the neurological damage characterizing Alzheimer’s disease in experimental animal model. This study was conducted on ninety adult female Sprague-Dawley rats weighing 100-120 g. The animals were classified into three main groups, the first group was gonad intact control group, the second group was ovariectomized-treated group which was divided into four subgroups and the third group was aluminum-intoxicated ovariectomized-treated group which was divided into four subgroups as follows: Group (I): Gonad intact control (nonovariectomized) group-treated with vehicle (Dimcthylsulfoxidc (DMSO) 5% in saline) three times weekly for 18 weeks after six months of starting the experiment. Group (11): Ovariectomized-treated group including 40 ovariectomized rats were divided equally into the following subgroups: Subgroup (A): Ovariectomized control group-treated with vehicle (DMSO 51’0 in saline) three times weekly for 18 weeks after six months of surgical operation.Subgroup (8): Ovariectomized rats in this group were injected subcutaneously with estrogen three times weekly in a dose of 80 ).lg/Kg b.wt. dissolved in DMSO 5% in saline for 18 weeks, after six months of surgical operation.