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العنوان
Diagnosis Of Polycystic Ovary Syndrome By Three-Dimensional Transvaginal Ultrasound /
المؤلف
El Fahar, Eman Ali Ahmed,
هيئة الاعداد
باحث / Eman Ali Ahmed El Fahar
مشرف / Ahmed Ahmed Salem
مناقش / Ahmed Mohamed Mansour
مناقش / Ashraf Nassif. M. El Mantwi
الموضوع
Obstetrics and Gynecology.
تاريخ النشر
2012.
عدد الصفحات
150p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة بنها - كلية طب بشري - النساء والتوليد
الفهرس
Only 14 pages are availabe for public view

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from 79

Abstract

Polycystic ovary syndrome is a heterogeneous disorder which has different definitive description because of the varied combination of clinical, biochemical and ultrasonographic features which may occur.
The ESHRE/ASRM Rotterdam 2003 criteria stated that polycystic ovaries syndrome could be diagnosed by having two of the following three features, after the exclusion of related disorders: (a) oligo-ovulation or anovulation, (b)clinical and/or biochemical signs of hyperandrogenism, or (c)ultrasound features of polycystic ovaries (The Rotterdam ESHRE/ASRM., 2004).
The 2003 Rotterdam Consensus Workshop defines ultrasonographic criteria for polycystic ovaries as the ”Presence of 12 or more follicles in each ovary measuring 2-9mm in diameter, and/or increased ovarian volume (>10mL)”.Only one ovary fitting this definition is sufficient to define polycystic ovaries.
There is no doubt that three dimensional ultrasound is a new imaging modality that allows quantitative assessment of follicular number and true volumetric calculation of the ovary.
In this study: twenty women presented to the Gynecological Outpatient Clinic at Banhe University Hospital, were recruited. Women were divided into two groups:
Polycystic ovaries group: 10 women diagnosed as polycystic ovaries syndrome, by having clinical features and laboratory results of polycystic ovaries syndrome. Anovulation is defined by history of chronic anovulation defined as amenorrhea for ≥3 months duration or oligomenorrhea (i.e.,intermenstrual intervals greater than 35 days).
Serum progesterone levels<3.0ng/ml at day 24 in the cycles. Clinical and/or biochemical signs of hyperandrogenism (Ferriman-Gallwey score >7 and/or testosterone level >0.5ng/ml).
Control Group:10 women ,they all had regular menstrual cycles ranging from 21-35 days with Ferriman-Gallwey score <7 with normal testosterone leve.
Comparison between both groups regarding patients characteristics and ultrasound measurements using two dimensional ultrasound for calculation of ovarian volume then three dimensional ultrasound for measurement of follicle number per ovary and maximum follicle number in single sonographic plane was performed.
There was statistical significant difference (P < 0.001) as regards body mass index, total testosterone, Ferriman-Gallwey score, and cycle day 24 progesterone between study and control group. No statistical significant difference was found between study and control group as regarding age and fasting blood glucose
Follicle number per ovary and follicle number per single sonographic plane were statistical significant higher among polycystic ovaries group compared to control group using three dimensional transvaginal ultrasound. Also ovarian volume was statistical significant higher among polycystic ovaries group compared to control group using two dimensional transvaginal ultrasound. Follicle number per ovary at cut off 18 using three dimensional transvaginal ultrasound has the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy 70%, 100%, 100.0%,76,9%, and85% respectively for diagnosis of polycystic ovari
Maximum follicle in single sonographic plane at cut off 9 has the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy 90%, 100%, 100.0%, 90,9%, and95% respectively. And also ovarian volume at cutoff 12 has the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy 50%, 100%, 100.0%, 66,7%, and75% respectively.