الفهرس 
Introduction and Aim of the workOnly 14 pages are availabe for public view
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Abstract
Neurological complications are among the central problems in DM.
Most diabetic patients are affected by neurological disorders. Vascular
dysfunction plays a major role in many complications associated with
diabetes.
Diabetic neuropathy and neurovascular complications represent a
major health problem. Therefore, Considerable attention has been directed to
explore new therapeutic strategies which can reduce hyperglycemia and
associated neurovascular complications.
The present work aimed mainly to:
I. Clarify the adverse effects of diabetes on neurovascular outcomes as
well as to address the molecular mechanisms underlying them.
II. Evaluate the effect of Resv, either as monotherapy or in combination
with Rosi and/or Rosu, on modulating neurovascular complications in
diabetic and diabetic brain IR rats.
III. Investigate the histological changes in cerebral tissue of diabetic and
diabetic brain IR rats.
IV. Identify the possible correlations between hyperglycemia,
cerebrovascular markers and the other studied parameters.