الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 163 |  |  |
| | | from | 163 | | |
Abstract
The concept of risk factors has evolved only over the past 45 years or so, and new factors are periodically added to the list as our comprehension of the disease process grows. To understand who is at risk and what risk actually means to an individual, one first needs to understand how CAD develops.
A cardiovascular risk factor is a condition that is associated with an increased risk of developing CVD .The epidemiological studies selecting a group that is representative of the population to which the information will later be applied.
Major risk factors are those that research has shown significantly increase the risk CVD. Other factors are associated with increased risk of CVD, but their significance and prevalence have not yet been precisely determined. They are called contributing risk factors.
Metabolic syndrome is a cluster of risk factors that is responsible for much of the excess CVD morbidity among overweight and obese patients and those persons with type 2 diabetes mellitus. Differences in body-fat distribution (i.e., gynecoid versus android) associated with an altered metabolic profile were documented in the medical researches.
The aim of this study was to study the pattern of risk factors profile in a sample of Egyptian patients with ischemic heart disease,
To achieve such target, our study was carried on a (905) subjects representing a sample of Egyptian population with different demographic characters including gender, age, socioeconomic state and residency. The subjects were recruited from 12 centers allover Egypt .The study also include subjects as a control group matched for age and gender, the selected individuals were divided into three groups: Group 1(700 ACS patients), Group2 (100 chronic stable angina patients) and the third group (group 3) include 105 individuals as a control group.
Our present study showed that:
Regarding the age: the mean age (in years) was 48.01± 10.66, 47.81 ±7.13and 45.77 ± 8.44 in group1, 2and3 respectively (p value 0.1).
Regarding the gender of patients, the ACS group included 545 male (77.9%) and 155 female (22.1%). Chronic stable angina group included 70 male (70%) and 30 female (30%), the control group included 65 male (61.9%) and 40 female (38.1%) p value 0.001.
The present study showed that: among Egyptians, there were significant positive correlation between HTN, DM type 1, DM type 2, dyslipidemia, family history of CAD and smoking in one hand and increased risk of CAD on the other.
There were significant positive correlation between total cholesterol, LDL, TG and occurrence of the disease, while there was significant negative correlation between HDL and increased risk of CAD.
Females of the ACS group had higher total cholesterol, HDL, LDL and TG, compared to males in the same group.
Males of chronic stable angina group had higher total cholesterol, HDL, LDL and TG, compared to females in the same group.
In this present study, were significant positive correlation between weight, waist circumference and hip circumference and increased risk of CAD.
Females showed a higher BMI in the three studied groups when compared to males. In the ACS group female had BMI of 30.7 vs. 28.4 for males p value <0.000. In the chronic stable angina group females had BMI of 33.9 vs. 30.2 for males the p value was 0.003.
Conclusion:
from the above mentioned results we can conclude that:
The Egyptian females had IHD particularly ACS at older age than males by at least 2 to 4 years later.
We found that gender, smoking, HTN and DM type 2 are significantly affecting the occurrence of disease among the studied groups.
There were significant positive correlation between HTN, DM type 1, DM type 2, dyslipidemia, family history of CAD and smoking in one hand and increased risk of CAD on the other.
There were significant positive correlation between total cholesterol, LDL, TG and occurrence of the disease, while there was significant negative correlation between HDL and increased risk of CAD.
There were significant positive correlation between weight, waist circumference and hip circumference and increased risk of CAD.
Ladies with ACS are obese when compared to males of the same group.