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العنوان
Asessment Of Osteopontin Level In Patients With Acute Coronary Syndrome /
المؤلف
ABU BAKR, OSAMA MOHAMED
هيئة الاعداد
باحث / OSAMA MOHAMED ABU BAKR
مشرف / ABDALLAH MOSTAFA KAMAL
مشرف / ELSAYED SABER ABOELNOUR
مشرف / HOSAMELDIN MAHMOUD
الموضوع
Cardiology.
تاريخ النشر
2012.
عدد الصفحات
178 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
16/9/2012
مكان الإجازة
جامعة المنوفية - كلية الطب - CARDIOLOGY
الفهرس
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Abstract

This study was done to find out the diagnostic value of
osteopontin among patients with acute coronary syndrome .
40 patients with acute coronary syndrome , 20 patients with
chronic stable angina were included in this study and 20 Normal
persons as control group they were subjected to complete medical
history, full clinical examination; ECG; laboratory investigations
include (CPK , CKMB , troponin-I, osteopontin) and routine
laboratory investigation .
60 patients were included in this study in two groups and
20 normal persons were included as control group, 40 patients
were included as group A with Acute coronary syndrome, 28
(70%) were male and 12 (30%) were female . 20 patients were
included as group B 13 (65%) were male and 7(35%) were
female .
In group A 19 patients (47.5% ) were smokers, 26patients
(65%) were diabetic, 22 (55%) were Hypertensive . 23(57.5%)
were dyslipidemic and 34(85%) were presented by typical chest
pain
In group B 5 patients (25%) were Smokers, 9 patients(45%)
were diabetic 10 patients (50%) were Hypertensive, 7 patients
(35%) were dyslipidemic and 12 patients (60%) were presented
by typical chest pain .
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Our study showed that the range of serum level of
osteopontin in group A is 0.9 - 22.9 and that the range of serum
level of osteopontin in group B is 0.23 – 4.7
These findings showed that serum level of osteopontin
group A is significaly higher than group B and the normal control
group
P value is significance = 0.001
the diagnostic accuracy of ostopontin = 86.7 %
the specificity = 100%
the sensitivity = 80 %
Our study demonstrated that raised level of osteopontin was
common in patients with Acute coronary syndrome and it is
useful as a diagnostic test .