الفهرس 
Introduction & Aim of The WorkOnly 14 pages are availabe for public view
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Abstract
Aging has a profound effect on the different eye structures including ocular lens, retina and optic nerve. The present work aimed to make a comparative study to highlight the effect of aging in different 3 classes of animals (Reptiles: Uromastyx aegyptius, Aves: Falco tinnunculus and Mammals: Rattus novergicus). The scanning electron microscopy reveals different changes of main body lens fibers with aging and hazardous effect of aging on the tight junctions of lens fiber sheets. In addition to marked decrease in lenticular amino acids.
Directing to the retina and optic nerve, there were different changes between their structures among different vertebrates. The light and electron microscopy show degeneration of retinal photoreceptor cell layers and ganglionic cells. Beside marked vaculation and degeneration of optic nerve fiber axons and dysfunction of its mitochondria. These effects were supported with genomic DNA fragmentation and COMET assay with marked depletion in antioxidant and neurotransmitter activity with aging.