الفهرس 
Introduction & Aim of the Work:Only 14 pages are availabe for public view
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Abstract
This study included 63 individuals divided into three groups:
Group I: 21 patients with CRF on conservative treatment.
Group II: 21 patients with CRF on regular hemodialysis.
Group III: 21 apparently healthy subjects of matched age and sex (as
control group).
All patients and controls were subjected to the following
investigations:
Routine investigations:
1- Fasting blood glucose level (FBG).
2- Renal function tests (serum urea and creatinine).
3- Liver function tests (ALT, AST, serum albumin and total
protein).
4- Lipid profile (serum total cholesterol and triglycerides).
5- CBC.
6- Erythrocyte sedimentation rate (ESR).
7- C- reactive protein (CRP).
Special investigations:
1- plasma Ghrelin level by Enzyme Immunoassay (EIA).
Results of different groups were compared with each other and
2- were summarized as follows:
3- 1- Group I and group II had statistically significant decrease in
4- BMI when compared to group III (P-value = 0.001).
5- 2- There was a statistically significant reduction in hemoglobin (Pvalue
6- <0.001), total protein (P-value <0.001, P-value = 0.03) and
7- albumin (P-value <0.001). when comparing group I and II to group III.
8- 3- There was a statistically significant elevation in CRP (P-value
9- <0.001, P-value = 0.002 ), 1st hour ESR (P-value <0.001) and 2nd hour
10- ESR (P-value <0.001). when comparing group I and II to group III.
11- 4- There was a statistically significant elevation in urea (P-value
12- <0.001), creatinine (P-value <0.001) and plasma ghrelin (P-value
13- <0.001). when comparing group I and II to group III.
14- 5- There was a statistically significant negative correlation between
15- plasma ghrelin and albumin in group I (r = -0.52 , P-value =0. 01) and
16- group II (r = -0.78 , P-value <0.001) and total protein in group II ( r = -
17- 0.62 , P-value =0. 003).
18- 6- There was a statistically significant positive correlation between
19- plasma ghrelin and creatinine in group II (r = 0.54 , P-value =0. 01)