الفهرس 
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Abstract
The molecular structure of 178 was indicated by its IH NMR spectrum, with these spectroscopic data the proposed linear structure of 178 is identified. In the angular structure 179 of the pyridine proton signal should have appeared at a higher field.
P,ng{isli Summary
We also studied the alkylation of 178 with ethyl iodide. reaction was carried out at r. t. in DMF and in the presence anhydrous potassium carbonate to afford the ethylated derivative 18J The structure of the product 183 was proved by elemental analysis an spectral data. This compound is not the O-ethylation product.
we report a novel and efficient one-pot method for the synthesis of pyrimido[5,4-b ]quinolin-2,4,9-trione and pyrimido[5,44c]isoquinoline derivatives with the purpose of investigating in the future their possible biological activity. The mechanism has been proved via synthesis of a proposed intermediate.
The reaction of 5-aminouracil (5), dimedone (165) and paraformaldehyde (177) in DMF and in the presence of triethylamine as a catalyst gave a solid product of the the pyrimido[5,4-b ]quinolinn2,4,9-trione 178.
The structure of compound 186 was confirmed by an independent synthesis of the same compound from an equimolar amounts of 5 and 2-dimethylaminomethylidenecyclohexane-l ,3-dione (185), in DMF under reflux to afford a product identical in all aspects to compound 186.