الفهرس 
DyslipidemiaOnly 14 pages are availabe for public view
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Abstract
Dyslipidemia is an important correctable, risk factor for coronary artery disease. There is strong, independent, continuous and graded relationship between total cholesterol or LDL cholesterol level and risk for coronary artery disease events.
The size of the lipid pool within an atherosclerotic plaque and the thickness of the overlying fibrous cap are important characteristics predicting the stability of advanced plaques. It is also known that vulnerable plaques are characterized by a large lipid pool with thin fibrous cap which is noted mostly with elevation of the lipid profile parameters.
In our study we used coronary MDCT scan to evaluate 50 patients of mean age 56.68 ± 9.25, male to female ratio 1.5:1 and with intermediate pretest propability for coronary artery disease along with full fasting lipid profile analysis.
MDCT scan allowed to evaluate number, site, volume and density of coronary artery plaques, more over it allowed their classification according to the type of plaques (calcified, mixed or non-calcified), significance of stenosis, eccentricity and remodeling.
We found that total serum cholesterol, LDL cholesterol and serum triglycerides were higher in the subgroup having non-calcified plaques than those with mixed or calcified ones and significantly higher in the subgroup with significant than those with non-significant stenosis. These three parameters demonstrated also a highly significant negative correlation with the mean density of the plaques, whereas no correlation was found with the type of remodeling.
HDL cholesterol was lower in the subgroup having non-calcified plaques than those with mixed or calcified ones and had significant positive correlation with the mean density of the plaques. whereas, it had no correlation with either the significance of stenosis or the type of remodeling.