الفهرس 
Basic physics of high frequency ultrasound imagingOnly 14 pages are availabe for public view
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Abstract
Ultrasound biomicroscopy is an imaging technology that uses high- frequency ultrasound and thus allows visualization of the anterior portion of the globe in microscopic resolution. Ultrasound biomicroscopy (DICON P45 UBM plus) has a 50 MHz transducer. This allows resolution of structures up to 50 microns. It is independent on the clarity of the optical media and allows, for the first time, a non-invasive demonstration of the structures of the anterior segment and their relationship to each other. Therefore, it is especially suitable for diagnosis and research on the various forms of glaucoma.
Ultrasound biomicroscopy is used to study the functional anatomy of the filtering bleb using high frequency (50 MHz) probe, which provides high- resolution images of filtering blebs. It was possible to obtain longitudinal or transverse images of filtering blebs, to measure the height, to evaluate the reflectivity inside and to follow the route under the scleral flap, so a correlation between bleb shape and intraocular pressure could be evaluated in glaucomatous patients treated with trabeculectomy with and without mitomycin.
The blebs of mitomycin tend to be morphologically high with thin wall, diffuse, avascular and may be polycystic. The IOP pressure was significantly statistically reduced with mitomycin in comparison to control group. UBM describes the internal structure of the filtering blebs, the height, the breadth and aqueous drainage route.
The mitomycin effect was evident in reducing the IOP pressure by affecting the internal structure of its blebs making it with higher height, breadth, more visible aqueous drainage route and lower reflectivity in comparison to cases performed without MMC.