الفهرس 
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Abstract
The preterm labor is a greater risk problem for the mother and baby. The aim of this study was to examine the impact of developing clinical guidelines on nurses’ knowledge and nursing management of preterm labor patients receiving tocolytics utilizing the evidence based practice. Data were collected in inpatient department in the following hospital 1- El-Tadamon Hospital, 2- Port Said General Hospital and 3- Suez Canal University Hospital .The sample divided to two part The first sample consisted of 40 nurses, the second sample205 of women who had used tocolytics in preterm labor The Search in systematic review, the data were collected through interviewing assessment sheet of nurse’s about knowledge and performance, develop the nursing care guidelines –Implementation of the guidelines – evaluation of the nurse’s performance. The main findings of this study were that: the knowledge of nurses improved from (4.79+1.735) in pre-test to (18.08+1.911) there is statistically significant , the performance of nurses improved from 20% in pretest to 85% in the post-test. there is statistically significant and two third of the sample (69.6%) delivered after two days. It recommended that every hospital should update the guidelines during the treatment of preterm labor with women who received tocolytics drugs.